Center for Antisocial Drug Dependence

This Center was funded to study genetic influences on, and treatment of, antisocial drug dependence, under a NIDA (DA 11015) grant. We represent a collaborative effort across two campuses of the University of Colorado, and the expertise of three research organizations:
  • The  of the , University of Colorado Health Sciences Center, Denver
  • The Institute for Behavioral Genetics of the University of Colorado at Boulder
  • The  of the University of Colorado at Boulder

Diagram depicting relationships between components 1-4 of CADD with genes, the brain, behavior, and pilot projects. Component 1 relates genes to behavior and the brain. Component 2 relates behavior to itself. Component 3 relates genes to the brain and the brain to behavior. Component 4 is the pilot studies.

Faculty:

  • John K. Hewitt
  • Thomas J. Crowley
  • Michael C. Stallings
  • Robin Corley
  • Marissa Ehringer
  • Ken Krauter
  • Susan Mikulich-Gilbertson
  • Soo H. Rhee
  • Gregory Carey
  • Stacey Cherny
  • Andrew Smolen
  • Susan Young
  • Matthew B. McQueen

Publication Highlights:

1. Hopfer, C.J., Lessem, J.M., Hartman, C.A., Stallings, M.C., Cherny, S.S., Corley, R.P., Hewitt, J.K., Krauter, K.S., Mikulich-Gilbertson, S.K., Rhee, S.H., Smolen, A., Young, S.E., Crowley, T.J. (2006). A genome-wide scan for loci influencing adolescent cannabis dependence symptoms: Evidence for linkage on chromosomes 3 and 9. Drug and Alcohol Dependence, 89, 34-41. 

2. Ehringer, M.A., Rhee, S.H., Young, S.E., Corley, R.P., Hewitt, J.K. (2006). Genetic and environmental contributions to common psychopathologies of childhood and adolescence: A study of twins and their siblings. Journal of Abnormal Child Psychology,34, 1-17. 

3. Stallings, M.C., Corley, R.P., Dennehey, B., Hewitt, J.K., Krauter, K.S., Lessem, J.M., Mikulich-Gilbertson, S.K., Rhee, S.H., Smolen, A., Young, S.E., & Crowley, T.J. (2005). A genome-wide search for quantitative trait loci influencing antisocial drug dependence in adolescence. Archives of General Psychiatry, 62, 1042-1051. 

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